ZOE Begone! is a hand-drawn bullet hell arcade shooter developed by Retchy Games, blending run-and-gun mechanics with classic shmup action. Players control Zoe as she fights through the creations of a pesky animator, utilizing shoot, dash, and pound actions within looping arenas. The game's aesthetic is inspired by 1930s drawn-on-film animation, with unique art styles and hand-animated enemies for each level.

The game offers three distinct modes: a standard shmup action mode, a time-based challenge, and an extended boss rush. Players can select from three difficulty settings, and progress is supported by power-ups and upgrades purchased with collected Apples. A key mechanic is the enemy chain scoring system, rewarding aggressive play and quick enemy takedowns to maintain a multiplier. ZOE Begone! includes online leaderboards for competitive play and 55 Steam achievements.