The Infectious Madness of Doctor Dekker is a Lovecraftian murder mystery adventure game. Players assume the role of a psychiatrist tasked with solving the murder of Doctor Dekker by interviewing his patients. The game utilizes over 1600 full-screen HD video responses, allowing players to ask questions via free text input or select from suggested prompts. Multiple endings and storylines are present, with six main suspects and five side-quests. A randomly chosen murderer at the start of each playthrough enhances replayability, and the game holds a Guinness World Record for "The most Full Motion Video (FMV) in a videogame."The game is structured around five therapy sessions, where players interact with patients to uncover clues about Dekker's death and their individual bizarre problems, ranging from time manipulation to paranormal occurrences. Players must carefully consider their dialogue, as choices impact patient fates and the overall narrative. The game avoids traditional puzzles, focusing solely on questioning and evidence inspection, with automatic saves preventing players from backtracking. D'Avekki Studios Ltd, the developer, also created "Murderous Muses," "Dark Nights with Poe and Munro," and "The Shapeshifting Detective."