Escape First 2 is a multiplayer escape room puzzle game developed and published by OnSkull Games. It is the second entry in the Escape First series. The game can be played on virtual reality or desktop PC platforms and includes three distinct escape rooms: Psycho Circus Cont., The Torture Chamber, and Behind the Scenes. Players can engage in competitive, co-op, or solo play, with support for up to six players in team or versus modes.

The game allows for up to six players to cooperate in solving puzzles or compete in a "Versus" mode where each player is individually locked in and races to escape first. Escape First 2 supports full room-scale tracking with motion controllers for VR headsets like the HTC Vive and Oculus Rift, but it is also playable on desktop using keyboard and mouse or a gamepad. The three included escape rooms present unique environments and challenges for players to overcome.