Call of Heroes: Tower Defense is a 2D strategy game that blends classic Tower Defense mechanics with RPG elements. Players recruit and evolve unique heroes, each possessing distinct magical spells and abilities. These heroes can be equipped with crafted weapons, made from resources gathered during gameplay. The core objective is to defend the fairy kingdom from waves of invading creatures by strategically deploying heroes and utilizing their powers to prevent enemies from reaching a magical portal.

The game features a detailed encyclopedia for lore and mechanics, a comprehensive tutorial, and multiple maps with varied terrain and obstacles. Its classic Tower Defense system is augmented with magical elements, requiring players to adapt strategies to different scenarios and enemy types.