Boxville 2 is an adventure game following cans inhabiting a box city. The narrative centers on two can friends tasked with setting up fireworks for a city celebration; a mishap leads to chaos and one friend's disappearance, prompting the red can protagonist to explore Boxville and its surroundings to rectify the situation and locate his companion.

The game utilizes hand-drawn graphics and custom animations for all characters and backgrounds. Each scene is complemented by a unique music track, and the gameplay incorporates dozens of logical puzzles and mini-games. Character communication occurs solely through speech bubbles, without spoken dialogue.