Bioweaver is an indie RPG where players, as a scientist in an underground lab, must craft a path to the surface by utilizing the organs and genes of escaped creatures. The game focuses on treasure hunting and character building, with a deep skill customization system that employs programming logic for organ linking.

Players can craft hundreds of organs, each with distinct attributes and functions, and further enhance them through mutations that introduce unpredictable changes. Bioweaver includes an adaptive difficulty system and offers post-main act challenges and additional exploration content.