Anomaly: Warzone Earth is an action-strategy hybrid that reverses the tower defense formula, placing players in the role of the attacker. The game involves leading an armored squad through near-future cities to repel an alien invasion that has established fortified positions. Players control the Commander, utilizing special abilities and strategic unit deployment to overcome enemy turrets. The game includes a story campaign and two Squad Assault Modes, emphasizing tactical resource management for unit upgrades.

The core gameplay loop centers on planning routes and selecting units to assault alien strongholds. Resource management is crucial for acquiring and upgrading the squad during battles. Anomaly: Warzone Earth was developed and published by 11 bit studios, known for their work in the strategy genre.