Amoeba Battle is a real-time strategy game developed by Grab Games. It redefines the genre by having players control amoebas that replicate through binary fission instead of constructing traditional bases. Players must feed their amoebas to enable replication, doubling their forces, and can introduce mutations to evolve them into stronger species with unique adaptations. The game incorporates four distinct, exotic landscapes rendered in a watercolor and pixel art style.
The title includes a single-player story campaign with adjustable difficulty levels and a co-op roguelike campaign mode called "Outbreak" that features randomized worlds and missions for high replayability. Multiplayer options consist of an 18-player cross-platform Battle Royale Versus mode and Skirmish against AI, playable solo or with friends. Players can leverage species-specific adaptations, terrain features, and deployable probes to gain tactical advantages.